Abstract: The relationship of flood control and water storage in three major reservoirs such as Xinfengjiang, Fengshuba, and Baipenzhu reservoirs in the Dongjiang River Basin needs a comprehensive consideration during flood seasons. Confirming the critical period of flood control and water storage in the three major reservoirs, and coordinate upstream and downstream flood security, via flood regulation routing to get a safe water level, combine the water consumption in dry seaon which considering regulation performance of reservoir, to finally get a optimal water level of the reservoirs. Relevant conclusions may be important guidance to the operation of the three reservoirs and improvement of the water security of Dongjiang River Basin.