Abstract: With the acceleration of urbanization, flood and waterlogging disasters occur frequently. In order to fundamentally solve the problem of urban flood and waterlogging, it is necessary to carry out flood and waterlogging safety assessment in the planning and design stage. Taking the Xiaohai river area of Conghua in Guangzhou city as an example, a two-dimensional coupling model based on InfoWorks ICM is constructed, three calculation methods of regulation and storage volume are proposed, and the flood and waterlogging safety after the planning and construction of the area is evaluated from the aspects of flood prevention and waterlogging. The analysis results show that after the planning and construction, the river system in this area has been partially adjusted, the overall water surface rate meets the standard, and the river basically meets the flood prevention requirements. After the planning and construction, the medium and high-risk areas of waterlogging in this area have increased significantly, but after the addition of regulation and storage facilities, the proportion of medium and high-risk areas of waterlogging has decreased greatly. As long as good daily management and emergency rescue work are carried out in this area, it can effectively resist the design rainstorm with a return period of 100 years and 24 hours.